---
title: Casualties Unknown LRD Serum, Braingrow, Mindwipe Guide
description: What L.R.D. serum, Braingrow, Mindwipe and the neural booster do, and when to use each.
url: https://casualtieswiki.wiki/items/lrd-braingrow-mindwipe/
---

Items

# Casualties Unknown L.R.D., Braingrow and Mindwipe
Which one, and when

- 1 **Bleeding inside, or badly hurt**L.R.D. serum

- 2 **Stroke, or falling brain health**Braingrow

- 3 **Stroke with no Braingrow**Mindwipe, as a last resort

- 4 **Late game upgrade**Neural booster, used carefully

_A decision aid from recordings and player reports on Demo 7.0.1. Exact effects are not officially published._

**Short answer:** in Casualties Unknown, **L.R.D. serum** is a strong general treatment that players credit with saving runs, **Braingrow** repairs brain damage and stops strokes, and **Mindwipe** is a last resort with serious side effects. Do not stack brain drugs close together. reported

These are among the most searched items in the game: `casualties unknown lrd` has about 1,123 monthly searches and Braingrow 585 (third-party estimates). Official patch notes say little about their numbers, so most detail here is reported by players, and the in-game item text should always win if it differs.

## What does L.R.D. serum do in Casualties Unknown?

L.R.D. is a serum players rely on after major injuries. On the Steam forum, one player says plain and makeshift L.R.D. “save runs”, and that you can get them within the first two layers if you are lucky or craft the makeshift version. reported Forum posts group it with other brewable drugs such as antidepressants, fentanyl and procoagulant. reported

Community pages say L.R.D. and procoagulant together are used for severe internal bleeding, with side effects that those two partly offset. unverified See [bleeding](https://casualtieswiki.wiki/health/bleeding-and-blood/) first if you are stacking it for that purpose.

### Where do you find L.R.D.?

- **Medical crates.** A popular guide opens one and finds L.R.D. in it. confirmed

- **Traders.** Recordings show it for sale. confirmed

- **Crafting**, for the makeshift version. reported

## What does Braingrow do in Casualties Unknown?

Braingrow is the go-to item when a [stroke](https://casualtieswiki.wiki/health/heart-and-stroke/) or [brain damage](https://casualtieswiki.wiki/health/brain-damage/) happens. A co-op recording shows a player point out that a stroke will kill you unless you have Braingrow. confirmed Another, mid-crisis, says simply “I need a Braingrow”. confirmed

Community pages list a quick cure for strokes and some brain health back, but with a chance of vomiting and a mood penalty. unverified Since 7.0, stroke-reducing items no longer repair your vision as well. confirmed

## What does Mindwipe do?

Mindwipe is what you take if you have nothing else. In [one recording](https://www.youtube.com/watch?v=55E9MII4pBQ&t=11191s), a player with a stroke says all they have to cure it is a Mindwipe, and treats that as a terrible option. confirmed Players also joke about what happens when someone drinks one by mistake. confirmed

Questions like `what does mindwipe do` are common, because the name suggests something frightening and the item is often found in loot. We cannot confirm exact effects from an official source. Assume you will lose something valuable, and only use it when the alternative is death. unverified

## What is a neural booster?

A late-game medical item. It can be crafted, and a recording shows a group excited to find the recipe. confirmed Community pages list it as stopping strokes, granting wide buffs and restoring some brain health the first time. unverified They also say that using one too soon after another brain drug carries a heavy penalty, so read the warning below.

Players warn against taking Braingrow or a neural booster shortly after one another. Community pages say doing so within a short window can trigger a Mindwipe-like effect, and that a moodle warns you while the risk is active. Check your moodles before a second dose. unverified

## How do Casualties Unknown crystals compare?

Crystal shards offer passive benefits while carried, which is useful if you do not want to spend drugs. Players search for several by name. Reported effects include: unverified

| Shard | Reported effect |
| --- | --- |
| Blood crystal | Slows blood loss |
| Digestion crystal | Slowly reduces sickness |
| Emissive crystal | Bright light while carried |
| Oxygen crystal | Helps with oxygen |
| Relief and soothing crystals | Mood or pain relief |

## Which should you save, and which should you use?

| Situation | Best choice | Why |
| --- | --- | --- |
| A stroke, any time | Braingrow | Few other treatments stop it |
| A big internal bleed | L.R.D. plus procoagulant | Players use the pair together |
| Small brain damage | Rest | Save your Braingrow |
| Dying with no options | Anything left | The run is ending anyway |
| Low on trade goods | Sell spares | These items have high trade value |

## Can you make these in Casualties Unknown?

Players report that bio-chem fluid, the game’s general crafting liquid, can produce several drugs, including L.R.D. serum, depending on your recipes and Intelligence. reported Recipes and their requirements appear in your crafting window, and blueprints unlock more, as the [crafting guide](https://casualtieswiki.wiki/items/crafting/) explains. Because the full game brings “a truckload of balance changes”, check recipes in your own game.

## Sources
Last checked 9 November 2026. Marks: confirmed = official notes, in-game text or a recording of the game; reported = two or more players; unverified = one source.

- [Steam forum: How to be successful?](https://steamcommunity.com/app/4576490/discussions/0/563667534781362619/) · L.R.D. saving runs

- [Tricks I Wish I Knew Sooner by BluePawClaw](https://www.youtube.com/watch?v=BLuLBHlRjIQ&t=164s) · medical crate

- [Recording: Braingrow and stroke](https://www.youtube.com/watch?v=jlWEic3AhFY&t=1614s) · 26:54

- [Recording: Mindwipe for a stroke](https://www.youtube.com/watch?v=55E9MII4pBQ&t=11191s) · 186:31

- [Recording: Neural booster recipe](https://www.youtube.com/watch?v=nul9_3tCqnw&t=8916s) · 148:36

- [7.0 Demo Update notes, Steam](https://steamstore-a.akamaihd.net/news/externalpost/steam_community_announcements/1834602721186794)

- [Steam forum: Splatter your game knowledge here!](https://steamcommunity.com/app/4576490/discussions/0/801219948950225874/)

## More in Items

- [Medicine and drugs What each medicine does, which drugs players rate highly and which ones can kill you.](https://casualtieswiki.wiki/items/medicine-and-drugs/)

- [Crafting How crafting works, how Intelligence limits it, and which recipes to make first.](https://casualtieswiki.wiki/items/crafting/)

- [Liquids and containers How to mix and separate liquids, which containers to use and how inventory slots work.](https://casualtieswiki.wiki/items/liquids-and-containers/)

- [Weapons and armor Which weapons to use, how fights work, and how armor protects your body.](https://casualtieswiki.wiki/items/weapons-and-armor/)

- [Tools and light Light sources, how to get batteries, lockpicking and the tools worth carrying.](https://casualtieswiki.wiki/items/tools-and-light/)